Diphtheria (Corynebacterium diphtheriae)

Corynebacteria are Gram-positive, aerobic, nonmotile, rod-shaped bacteria related to the Actinomycetes. They do not form spores or branch as do the actinomycetes, merely they ware the trace of forming irregular shaped, club-shaped or V-shaped arrangements in frequent growth. They endure snapping movements just after cell division which brings them into characteristic arrangements resembling Chinese letters. The genus Corynebacteria consists of a respective(a) group of bacteria including animal and do pathogens, as head as saprophytes. Some corynebacteria are pop of the normal flora of piece, finding a suitable niche in virtually every anatomical site. The best know and most widely canvas species is Corynebacterium diphtheriae, the causal broker of the distemper diphtheria. History and Background No bacterial disease of humans has been as success plenteousy studied as diphtheria. The etiology, mode of transmission, infective mechanism and molecular terra firma of ex otoxin structure, function, and action have been clearly established. Consequently, highly effective methods of treatment and prevention of diphtheria have been developed. The study of Corynebacterium diphtheriae traces most the development of medical microbiology, immunology and molecular biology. Many contributions to these fields, as well as to our understanding of host-bacterial interactions, have been made studying diphtheria and the diphtheria toxin. Hippocrates provided the low clinical description of diphtheria in the 4th century B.C.

thither are also references to the disease in ancient Syria and Egypt. In the 17th century, murderous epidemics of! diphtheria swept Europe; in Spain El garatillo (the strangler), in Italy and Sicily, the gullet disease. In the 18th century, the disease reached the American colonies and reached epidemic proportions in 1735. Often, whole families died of the disease in a a few(prenominal) weeks. The bacterium that caused diphtheria was first described by Klebs in 1883, and was accomplished by Loeffler in 1884, who applied Kochs postulates and properly identified Corynebacterium... If you indigence to get a full essay, order it on our website: OrderCustomPaper.com

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